Freedom fromKnee Pain
What are Hyaluronic Acid / PRP Knee joint Injections?
Viscosupplementation therapy that replenishes the natural cushioning in your knee joint, combining high-molecular-weight hyaluronic acid with powerful antioxidants for optimal results.
Fast-Acting Relief
Experience pain reduction within 3-7 days of treatment with continued improvement over weeks
Long-Lasting Results
Symptom relief lasting 6 months or more with just a single or short-course treatment
Excellent Safety Profile
Swiss-engineered formulation with minimal adverse events and proven clinical efficacy
Improved Mobility
Restore joint function and quality of life through enhanced lubrication and shock absorption
How It Works
Professional Assessment
Consultation and imaging confirmation of osteoarthritis grade
Treatment Session
Single 4ml injection or three weekly 2ml injections administered by qualified specialists
Recovery & Results
Mild rest for 48-72 hours, with symptom improvement within 3-7 days
Who Is Suitable?
Individuals with knee or hip osteoarthritis
Those who cannot tolerate NSAIDs or corticosteroids
Patients preferring to defer or avoid surgery
Those seeking non-pharmacological therapy options
Expected Outcomes
of patients experience significant improvement
average pain reduction reported
weeks to reach peak benefits
months of sustained relief
Based on clinical studies and patient outcomes
Understanding Osteoarthritis on X-Ray
X-ray imaging reveals key structural changes in osteoarthritic knees that help guide treatment decisions
Left: Normal knee joint | Right: Osteoarthritic changes
Key X-Ray Changes in Osteoarthritis
Joint Space Narrowing
Reduction in the space between bones due to cartilage loss, indicating progressive osteoarthritis
Osteophytes Formation
Bone spurs that develop at joint margins as the body attempts to repair damaged cartilage
Tibial Spiking
Sharp bony projections at the tibial plateau edge, characteristic of advanced joint degeneration
Joint Irregularity
Uneven bone surfaces and subchondral changes reflecting chronic wear and inflammation
Clinical Note: These X-ray findings help determine the severity of osteoarthritis and guide treatment planning, including the suitability for hyaluronic acid and PRP injection therapy.
Ready to Take the Next Step?
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RegenPRP® Therapy: Advanced Platelet-Rich Plasma Treatment
Harness your body's natural healing power with RegenPRP® injections. This scientifically validated regenerative medicine approach uses concentrated growth factors from your own blood to promote tissue repair and reduce knee pain without synthetic drugs or surgery.
What is RegenPRP®?
RegenPRP® represents a leukocyte-reduced PRP system, engineered to enhance healing through high concentrations of viable platelets and minimal pro-inflammatory cells. Backed by clinical research and precision Swiss engineering (RegenKit® THT), this therapy enables your body to repair and regenerate tissues naturally.
Unlike steroid injections which provide short-term pain relief, RegenPRP® heals the underlying pathology by stimulating stem cell migration, collagen synthesis, and new blood vessel formation— resulting in long-term tissue regeneration.
Natural Healing
Uses your own blood platelets to stimulate natural healing and tissue regeneration
Reduces Inflammation
Over 85% depletion of pro-inflammatory granulocytes for powerful anti-inflammatory effects
Promotes Tissue Repair
Growth factors accelerate cartilage and tendon healing through stem cell migration and collagen synthesis
Minimal Side Effects
Fully autologous - reduces risk of rejection or allergic reaction with no systemic side effects
The RegenKit® THT System: Swiss Precision Engineering
90%+ Platelet Recovery
Swiss-engineered RegenKit® THT system ensures maximum platelet concentration
85% Granulocyte Reduction
Minimizes pro-inflammatory white blood cells for optimal healing
Complete RBC Removal
Almost complete removal of red blood cells through precision centrifugation
Ultrasound-Guided
Physician-led injections for maximum accuracy and effectiveness
How RegenPRP® Treatment Works
Consultation & Diagnosis
Comprehensive musculoskeletal exam and ultrasound imaging for precise assessment
Blood Collection & Processing
~10ml blood drawn and processed through RegenKit® THT centrifuge system
Ultrasound-Guided Injection
Concentrated PRP injected precisely into damaged area under ultrasound guidance
Customized Rehabilitation
Tailored exercise protocol to enhance regeneration and optimize recovery
Treatment Protocol
Sessions
Typically 3 injections at weekly intervals
Downtime
Minimal - return to light activity in 24-48 hours
Side Effects
Mild soreness at injection site, no allergic reactions
Conditions Treated with RegenPRP®
Knee Osteoarthritis
Achilles Tendinopathy
Patellar Tendinopathy (Jumper's Knee)
Rotator Cuff Injuries
Tennis/Golfer's Elbow
Plantar Fasciitis
Gluteal Tendinopathy
Chronic Tendon Injuries
Clinical Evidence: RegenPRP® for Achilles Tendinopathy
Study Details
- • Design: Retrospective study with 44 patients
- • Condition: Recalcitrant non-insertional Achilles tendinopathies
- • Treatment: 3 RegenPRP® injections (4ml each) at weekly intervals
- • Follow-up: 1, 3, 6, and 12 months
- • Method: Ultrasound-guided, sterile conditions, no anaesthesia
Results
- • Consistent and statistically significant increase in VISA-A scores
- • Benefits observed across all follow-up time points
- • Younger patients (<55 years) showed more pronounced improvement
- • Long-term improvements in tendon function and pain relief
- • Sustained gains maintained up to 24 months post-treatment
Hyaluronic Acid vs RegenPRP®: Choosing the Right Treatment
| Feature | Hyaluronic Acid | RegenPRP® Therapy |
|---|---|---|
| Source | Synthetic or bioengineered hyaluronic acid | Your own blood platelets and growth factors |
| Primary Action | Lubricates and cushions the joint | Stimulates healing and reduces inflammation at cellular level |
| Duration | 6-12 months of relief | Long-term healing, benefits up to 24+ months |
| Best For | Mild to moderate osteoarthritis | Early to moderate osteoarthritis, chronic tendon injuries |
| Mechanism | Mechanical lubrication | Biological tissue regeneration and repair |
Combination Therapy Available
Many patients benefit from a combination of both RegenPRP® and Hyaluronic Acid injections. Hyaluronic acid provides immediate lubrication while PRP stimulates long-term healing. Dr Gerard Ee will assess your condition and recommend the most effective personalized treatment plan tailored to your specific needs and recovery goals.
Ready to Take the Next Step?
Get expert advice on your treatment options
Expert Medical Care
Dr Gerard Ee
MBBS, MRCS (Edinburgh), PG Dip Dermatology (Cardiff)
International Training
Medical degree from St George's University of London with surgical experience at Singapore General Hospital, National University Hospital, and Mount Sinai Hospital in New York
Specialized Expertise
Membership of the Royal College of Surgeons (Edinburgh) and Postgraduate Diploma in Dermatology. Fully accredited in advanced aesthetic and orthopedic procedures
Patient-Centered Approach
Focused on minimally invasive techniques with emphasis on creating subtle, natural results through evidence-based care and individualized treatment protocols
Evidence-Based Medicine
Dr Gerard Ee is a dedicated clinical researcher with multiple peer-reviewed publications in esteemed medical journals, including The Knee, Clinical Orthopaedics and Related Research, and the Journal of Orthopaedic Surgery and Research, where his work has contributed to advancements in knee arthroplasty, joint preservation, and computer-assisted surgery.
Computer navigation is a useful intra-operative tool for joint line measurement in total knee arthroplasty
This study found that joint line changes ≥4 mm during computer-assisted total knee arthroplasty (TKA) were associated with significantly poorer clinical outcomes. Computer navigation enabled precise intraoperative joint line assessment, helping improve surgical outcomes.
Authors: Gerard Ee, Hee Nee Pang, Hwei Chi Chong, Shi Lu Chia, Pak Lin Chin, Ngai Nung Lo, Mann Hong Tan, Seng Jin Yeo
Read Full PublicationMinimally invasive Unicondylar Knee Arthroplasty in a patellectomized patient
This case study demonstrates that partial knee replacement (UKA) using a minimally invasive approach can work well for patients who had their kneecap removed in the past, with excellent five-year outcomes showing no pain and normal walking.
Authors: Hee Nee Pang, Gerard Ee, Ngai-Nung Lo, Seng Jin Yeo
Read Full PublicationThe patellofemoral syndrome; the same problem as the Loch Ness Monster?
This publication highlights that 'patellofemoral syndrome' lacks a consistent clinical definition and fails to meet the criteria of a true medical syndrome. The authors advocate for using 'anterior knee pain' to describe the symptom without implying a specific pathology.
Authors: Ee Wen Wei Gerard, Ronald Grelsamer, Garrett Moss
Read Full PublicationDr Gerard Ee has honed his surgical skills at leading institutions such as National University Hospital and Singapore General Hospital, treating a wide range of knee disorders from sports-related injuries to degenerative joint disease using both surgical and non-surgical approaches tailored to each patient's needs.
Patient Success Stories
Real experiences from patients who found relief through our advanced knee treatments
"After struggling with knee pain for years, Dr Ee's hyaluronic acid treatment has been life-changing. I can now walk without pain and even started gardening again. The relief lasted over 8 months!"
Margaret L.
Age 68 • Hyaluronic Acid Injection
Pain reduced by 80%
"As an avid runner, my knee pain was affecting my quality of life. Dr Gerard Ee recommended PRP therapy, and within a few weeks, I noticed significant improvement. I'm back to running 5km three times a week."
David T.
Age 52 • PRP Therapy
Returned to active lifestyle
"Dr Ee suggested a combination of hyaluronic acid and PRP injections for my moderate osteoarthritis. The results exceeded my expectations. I avoided knee surgery and can now play with my grandchildren pain-free."
Susan K.
Age 61 • Combination Therapy
Avoided surgery, full mobility restored
Individual results may vary. Testimonials represent typical patient experiences but are not a guarantee of specific outcomes. Consult with Dr Gerard Ee to determine the most suitable treatment for your condition.
Ready to Take the Next Step?
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Latest Blog Posts
Stay informed with the latest insights on knee pain treatment and osteoarthritis management
Frequently Asked Questions
Get answers to common questions about hyaluronic acid knee injections
Ready to Experience Relief?
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Contact Information
The Clifford Clinic
50 Raffles Place
#01-01 Singapore Land Tower
Singapore 048623
(Exit B from Raffles MRT)
Phone
(65) 6532 2400Opening Hours
Mon to Fri: 10am to 8pm
Sat: 10am to 5pm
Closed on Sundays and Public Holidays
Book Your Consultation
Our specialists are ready to assess your condition and recommend the most suitable treatment plan for your knee pain. Get in touch today to schedule your appointment.
Why Choose Clifford Clinic?
- ✓ Expert orthopedic specialists
- ✓ Evidence-based treatment protocols
- ✓ Swiss-engineered formulations
- ✓ Personalized patient care
Visit Our Clinic
Conveniently located in the heart of Singapore's CBD
The Clifford Clinic
50 Raffles Place
#01-01 Singapore Land Tower
Singapore 048623
(Exit B from Raffles MRT)